September 10, 2018
KANEKA♦ KanCapA 3G sorbent comprises a recombinant Protein A ligand covalently attached to a rigid cellulose matrix. This ensures stability over a high number of cycles and provides high flow performance at low pressure making the sorbent compatible with the process requirements for large scale mAb manufacture in both batch and continuous processing using multi-column chromatography solutions. The sorbent is available in 1 and 5 mL PRC prepacked columns designed for rapid method optimization or small-scale preparative work and is also available in bulk as a slurry in 20% (v/v) ethanol in pack sizes ranging from 25 mL to 10 L.
Great dynamic binding capacity and long service life for improved process economy, gentle elution at a mild pH to protect against mAb aggregation or denaturation. Guard against impurities with high selectivity for efficient HCP and aggregate removal!