June 22, 2017
The Cadence™ BioSMB Process 350 system’s single-use flow path helps to reduce costs and the risks of cleaning and cleaning validation. Its highly configurable valve block with eight column positions also enables continuous loading resulting in best productivity, and reduces time and cost in terms of facility usage, buffers and chromatography media. A modular design allows for hardware configuration for a wider range of flow rates, thus reducing CAPEX costs, storage space and maintenance. Plus its scalable design offers a proven route from process development to manufacturing scale, reducing tech transfer risk and delivering the benefits seen at development scale.
Pall’s Cadence BioSMB platform provides a highly flexible multicolumn chromatography system that delivers high throughput and very efficient media utilization when compared to traditional batch and other continuous chromatography methodologies. This is achieved through a unique single-use eight column system architecture that enables highly flexible flow configuration through the single-use valve cassette. Additionally, the platform is fully scalable from process development (PD) to commercial manufacture.